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WON JO, M.D.
Harvard-trained gastroenterologist and hepatologist providing comprehensive and compassionate digestive care to adults in the Inland Empire
Dr. Jo grew up in Los Angeles and attended college at Duke University. After obtaining his M.D. degree from the University of California, San Diego, Dr. Jo performed his internship and residency at Tufts-New England Medical Center in Boston, Massachusetts. Dr. Jo completed his fellowship training in gastroenterology and hepatology at Massachusetts General Hospital, one of the two major hospitals affiliated with Harvard Medical School. Dr. Jo was engaged in colon cancer research and taught at Harvard Medical School during his fellowship. Dr. Jo has several publications in national journals regarding the genetics and treatment of colon cancer. Dr. Jo was on the medical staff at the University of California, San Diego and practiced in Laguna Hills, California before joining the San Bernardino and Redlands community in 2007.
Jo WS, Bandipalliam P, Shannon KM, Niendorf KB, Chan-Smutko G, Hur C, Syngal S, Chung DC. Correlation of polyp number and family history of colon cancer with germline MYH mutations. Clinical Gastroenterology and Hepatology. Vol 3 (10): 1022-1028, 2005.
Jo WS, Mizukami Y, Zukerberg LR, Chung DC. Wnt signaling can repress thrombospondin-1 expression in colonic tumorigenesis. Cancer Biology and Therapy. Vol 4(12):1361-6, 2005.
Mizukami Y, Jo WS, Gala M, Li J, Zhang X, Duerr EM, Zimmer MA, Iliopoulos O, Zukerberg LR, Lynch MP, Rueda BR, Chung DC. Induction of interleukin-8 preserves the angiogenic response in HIF-1 deficient colon cancer cells. Nature Medicine. Vol 11(9): 992-97, 2005.
Li J, Mizukami Y, Zhang X, Jo WS, Chung DC. Oncogenic K-ras increases nuclear β-catenin levels in a PI3-K dependent manner to stimulate Wnt signaling. Gastroenterology. Vol 128(7):1907-18, 2005.
Mizukami Y, Fujiki K, Duerr EM, Gala M, Jo WS, Zhang X, Chung DC. Hypoxic regulation of vascular endothelial growth factor through the induction of PI3K/ROCK and c-Myc. Journal of Biological Chemistry. Vol 281(20):13957-63, 2006.
Jo WS, Carethers JM. Chemotherapeutic implications in microsatellite unstable colorectal cancer. Disease Markers. Vol 2(1-2):51-60, 2006.
Jo WS, Chung DC. Genetics of hereditary colorectal cancer. Seminars in Oncology. Vol 32: 11-23, 2005.
Jo WS, Bandipalliam P, Shannon KM, Niendorf KB, Chan-Smutko G, Syngal S, Chung DC. Polyp number and family history are not reliable predictors of germline MYH mutations. Gastroenterology. Vol 128: A144 (889), 2005.
Mizukami Y, Jo WS, Gala M, Li J, Zhang X, Duerr EM, Zimmer MA, Iliopoulos O, Lynch MP, Rueda BR, and Chung DC. Activation of NF-kB and preservation of the angiogenic response in HIF-1 deficient colon cancer cells. Gastroenterology. Vol 128: A144 (T1445), 2005.
Li J, Mizukami Y, Zhang X, Jo WS, Chung DC. K-ras can inhibit GSK3-β and stimulate the Wnt signaling pathway in colon cancer. Gastroenterology. Vol 126: A262 (M925), 2004.
Carethers JM, Lopez BM, Zigman AF, Jo WS, Lavine JE, Jones MC, Chauhan DP, Chang CL, Appleman HD, Boland CR. Presence of microsatellite instability in normal-appearing epithelium of familial juvenile polyps. Gastroenterology. Vol 114: A574 (G2350), 1998.
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